Pepe's Cafe
Key West, Florida · Overseas Highway (Florida Keys)
Why stop here: Pepe's Cafe is a $$ american pick in Key West for Overseas Highway (Florida Keys) travelers. Order Apalachicola Oysters.
Key West's oldest eatery, open since 1909, a beloved breakfast and oyster spot in a shaded backyard courtyard.
Apalachicola Oysters
At Pepe's Cafe, Roamward highlights Apalachicola Oysters because it gives travelers a clear first order instead of leaving the meal to guesswork. Use it as the anchor, then check the current menu before you go.
Updated July 2026. Restaurant hours, menus, and reservation policies change — confirm before you go.
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